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Functional Contacts With A Range Of Splicing Proteins Suggest A Central Role For Brr2p In The Dynamic Control Of The Order Of Events In Spliceosomes Of Saccharomyces Cerevisiae

GENETICS, no. 4 (2001): 1451-1467

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Mapping of functional protein interactions will help in understanding conformational rearrangements that occur within large complexes like spliceosomes. Because the U5 snRNP plays a central role in pre-mRNA splicing, we undertook exhaustive two-hybrid screening with Brr2p, Prp8p, and other U5 snRNP associated proteins. DExH-box protein Br...更多

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