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Acetylation of insulin receptor substrate-1 is permissive for tyrosine phosphorylation.

BMC biology, no. 1 (2004): 23-23

被引用126|浏览4
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Insulin receptor substrate (IRS) proteins are key moderators of insulin action. Their specific regulation determines downstream protein-protein interactions and confers specificity on growth factor signalling. Regulatory mechanisms that have been identified include phosphorylation of IRS proteins on tyrosine and serine residues and ubiqui...更多

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