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Herpes Simplex Virus Protein Kinase U(S)3 Activates And Functionally Overlaps Protein Kinase A To Block Apoptosis

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, no. 25 (2004): 9411-9416

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Herpes simplex virus 1 encodes at least four genes whose functions include blocking apoptosis induced by exogenous agents (e.g., sorbitol, Fas ligand, and BAD protein) or replication-incompetent mutants (e.g., the d120 mutant lacking both copies of the alpha4 gene). U(S)3, one of these four genes, encodes a serine-threonine kinase that ha...更多

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