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Otx2 regulates subtype specification and neurogenesis in the midbrain.
JOURNAL OF NEUROSCIENCE, no. 19 (2005): 4856-4867
The transcription factor Otx2 is required to determine mesencephalic versus metencephalic ( cerebellum/ pons) territory during embryogenesis. This function of Otx2 primarily involves positioning and maintaining the mid- hindbrain organizer at the border between midbrain and anterior hindbrain. Otx2 expression is maintained long after this...More
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