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Identification Of A Novel Protein Kinase Mediating Akt Survival Signaling To The Atm Protein

JOURNAL OF BIOLOGICAL CHEMISTRY, no. 1 (2003): 48-53

Cited: 131|Views30

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pubmed.ncbi.nlm.nih.gov academic.microsoft.com

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geneprotein kinasecell cycle checkpointphosphorylationcloningMore(1+)

Abstract

We identified a novel human AMP-activated protein kinase (AMPK) family member, designated ARK5, encoding 661 amino acids with an estimated molecular mass of 74 kDa. The putative amino acid sequence reveals 47, 45.8, 42.4, and 55% homology to AMPK-alpha1, AMPK-alpha2, MELK and SNARE respectively, suggesting that it is a new member of the A...More

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