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Alpha-fetoprotein: the major high-affinity estrogen binder in rat uterine cytosols.

Proceedings of the National Academy of Sciences of the United States of America, no. 5 (1976): 1452-1456

Cited by: 54|Views5
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Abstract

Evidence is present that alpha-fetoprotein (AFP), a serum globulin, accounts mainly, if not entirely, for the high estrogen-binding properties of uterine cytosols from immature rats. By the use of specific immunoadsorbents to AFP and by competitive assays with unlabeled steroids and pure AFP, it has been demonstrated that in hypotonic cyt...More

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