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A Computational Study Of Off-Target Effects Of Rna Interference
NUCLEIC ACIDS RESEARCH, no. 6 (2005): 1834-1847
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摘要
RNA interference (RNAi) is an intracellular mechanism for post-transcriptional gene silencing that is frequently used to study gene function. RNAi is initiated by short interfering RNA (siRNA) of similar to 21 nt in length, either generated from the double-stranded RNA (dsRNA) by using the enzyme Dicer or introduced experimentally. Follow...更多
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