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Lsh, an SNF2/helicase family member, is required for proliferation of mature T lymphocytes

Proceedings of the National Academy of Sciences of the United States of America, no. 9 (2000): 4772-4777

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Lsh (Hells) is closely related to SNF2/helicase family members that remodel chromatin and thus regulate gene transcription. In the adult mouse Lsh is expressed primarily in lymphoid tissue, showing the highest level in thymocytes. Lsh gene expression can be induced in thymic pro-T cells by pre-T cell receptor crosslinking and in mature T ...更多

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