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Pooling, meta-analysis, and the evaluation of drug safety.
CURRENT CONTROLLED TRIALS IN CARDIOVASCULAR MEDICINE, no. 1 (2002): 6-6
Background: The "integrated safety report" of the drug registration files submitted to health authorities usually summarizes the rates of adverse events observed for a new drug, placebo or active control drugs by pooling the safety data across the trials. Pooling consists of adding the numbers of events observed in a given treatment group...More
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