SaP323 DO GUIDELINE-BASED COMPUTER PROMPTS IMPROVE CLINICAL PRACTICE IN DIALYSIS PATIENTS? - PRELIMINARY RESULTS OF ORAMA STUDY

are 0.36 vs.0.56 ml/min/100g body weight in F, 0.37 vs. 0.62 ml/min/100g body weight in M), with no influence of gender. Plasma renin activity was found to be reduced in both M and F SNX animals. Conclusions: In this model of mild renal insufficiency prominent gender effects on the degree of hypertension, cardiac remodeling and proteinuria were found. Compared to SNX M rats, F showed less hypertension, ventricular hypertrophy and dilatation. In contrast, M had less proteinuria indicating less renal injury than in the F. The results suggest that estrogens differently influence the progression of cardiovascular and renal diseases.