Probing the impact of the echinT C-terminal domain on structure and catalysis

Journal of Molecular Biology, pp. 627-638, 2010.

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Abstract:

Histidine triad nucleotide binding protein (Hint) is considered as the ancestor of the histidine triad protein superfamily and is highly conserved from bacteria to humans. Prokaryote genomes, including a wide array of both Gram-negative bacteria and Gram-positive bacteria, typically encode one Hint gene. The cellular function of Hint and ...More

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