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Ras-Associated Protein-1 Regulates Extracellular Signal-Regulated Kinase Activation And Migration In Melanoma Cells: Two Processes Important To Melanoma Tumorigenesis And Metastasis

CANCER RESEARCH, no. 16 (2006): 7880-7888

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Melanoma is one of the most devastating malignances with a rising incidence and lack of effective treatments for advanced disease. Constitutive activation of the mitogen-activated protein kinase (MAPK) pathway and altered expression of alpha(v)beta(3) integrin are critical for melanoma development and progression. Ras-associated protein-1...更多

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