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Persistent Cytomegalovirus-Specific Memory Responses in the Lung Allograft and Blood following Primary Infection in Lung Transplant Recipients1

JOURNAL OF IMMUNOLOGY, no. 4.0 (2006): 2625-2634

Cited: 56|Views27
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Abstract

Primary CMV infection in lung transplant recipients (LTRs) is associated with increased mortality. We studied 22 donor CMV-positive, recipient-negative (D+R-) LTRs for the development of posttransplant CNIV-specific immunity. We found that 13 of 22 D+R- LTRs (59.1%) seroconverted (CMV IgG Ab(+)). Using pooled peptides of the immunodominan...More

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