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Vaccinia Virus Entry into Cells via a Low-pH-Dependent Endosomal Pathway

JOURNAL OF VIROLOGY, no. 18 (2006): 8899-8908

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Previous studies established that vaccinia virus could enter cells by fusion with the plasma membrane at neutral pH. However, low pH triggers fusion of vaccinia virus-infected cells, a hallmark of viruses that enter by the endosomal route. Here, we demonstrate that entry of mature vaccinia virions is accelerated by brief low-pH treatment ...更多

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