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Long-Term Protective Effect Of Mature Dc-Lamp(+) Dendritic Cell Accumulation In Sentinel Lymph Nodes Containing Micrometastatic Melanoma

CLINICAL CANCER RESEARCH, no. 13 (2007): 3825-3830

Cited: 69|Views34
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Abstract

Purpose: In a previous immunohistochemical study of dendritic cells (DC) in sentinel lymph nodes (SLN) draining regressing melanomas, we found that the accumulation of mature DC-LAMP(+) DCs in SLNs was associated with local expansion of antigen-specific memory effector CTLs and the absence of metastasis in downstream lymph nodes. The aim ...More

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