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Laminin-332 Is A Substrate For Hepsin, A Protease Associated With Prostate Cancer Progression

JOURNAL OF BIOLOGICAL CHEMISTRY, no. 45 (2008): 30576-30584

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Hepsin, a cell surface protease, is widely reported to be over-expressed in more than 90% of human prostate tumors. Hepsin expression correlates with tumor progression, making it a significant marker and target for prostate cancer. Recently, it was reported that in a prostate cancer mouse model, hepsin up-regulation in tumor tissue promot...更多

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