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Aquaporin 1 Regulates Gtp-Induced Rapid Gating Of Water In Secretory Vesicles

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, no. 7 (2002): 4720-4724

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The swelling of secretory vesicles has been implicated in exocytosis, but the underlying mechanism of vesicle swelling remains largely unknown. Zymogen granules (ZGs), the membrane-bound secretory vesicles in exocrine pancreas, swell in response to GTP mediated by a G(alphai3) protein. Evidence is presented here that the water channel aqu...更多

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