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Guanosine reduces apoptosis and inflammation associated with restoration of function in rats with acute spinal cord injury.

Purinergic signalling, no. 4 (2007): 411-421

Cited: 60|Views21

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ApoptosisCell deathGliaGuanosineImmunohistochemistryMore(4+)

Abstract

Spinal cord injury results in progressive waves of secondary injuries, cascades of noxious pathological mechanisms that substantially exacerbate the primary injury and the resultant permanent functional deficits. Secondary injuries are associated with inflammation, excessive cytokine release, and cell apoptosis. The purine nucleoside guan...More

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