p190 Rho-GTPase activating protein associates with plexins and it is required for semaphorin signalling.
JOURNAL OF CELL SCIENCE, no. 20 (2005): 4689.0-4700.0
Plexins are transmembrane receptors for semaphorins, guiding cell migration and axon extension. Plexin activation leads to the disassembly of integrin-based focal adhesive structures and to actin cytoskeleton remodelling and inhibition of cell migration; however, the underlying molecular mechanisms are unclear. We consistently observe a t...更多
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