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Role Of Early Growth Response-1 (Egr-1) In Interleukin-13-Induced Inflammation And Remodeling

JOURNAL OF BIOLOGICAL CHEMISTRY, no. 12 (2006): 8161-8168

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IL-13 is an important stimulator of inflammation and tissue remodeling at sites of Th2 inflammation, which plays a key role in the pathogenesis of a variety of human disorders. We hypothesized that the ubiquitous transcription factor, early growth response-1 (Egr-1), plays a key role in IL-13-induced tissue responses. To test this hypothe...更多

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