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Production of recombinant antibody fragments in Bacillus megaterium.

Microbial cell factories, no. 1 (2007): 2-2

Cited: 105|Views29
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Abstract

Recombinant antibodies are essential reagents for research, diagnostics and therapy. The well established production host Escherichia coli relies on the secretion into the periplasmic space for antibody synthesis. Due to the outer membrane of gram-negative bacteria, only a fraction of this material reaches the medium. Recently, the gram-p...More

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