Dynamic Reorganization Of Chromatin Structure And Selective Dna Demethylation Prior To Stable Enhancer Complex Formation During Differentiation Of Primary Hematopoietic Cells In Vitro

In order to gain insights in the true molecular mechanisms involved in cell fate decisions, it is important to study the molecular details of gene activation where such decisions occur, which is at the level of the chromatin structure of individual genes. In the study presented here we addressed this issue and examined the dynamic develop...More