Epigenetic regulation of stem cell differentiation.
PEDIATRIC RESEARCH, no. 4 (2006): 21R-25R
Stem cells undergo extensive self-renewal and have the capacity to differentiate along Multiple cell lineages. Progression from stem cells into differentiated progeny requires long-lasting changes in gene expression. Epigenetic mechanisms, including DNA methylation, histone modifications, and non-coding RNA-mediated regulatory events, are...更多
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