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Still embedded together binding to membranes regulates Bcl-2 protein interactions.

ONCOGENE, no. 38.0 (2010): 5221-5230

Cited by: 95|Views6
WOS NATURE

Abstract

The dysregulation of apoptosis is a key step in developing tumours, and mediates resistance to cancer therapy. Many different signals for cell death converge on permeabilization of the outer mitochondrial membrane, which is controlled by the Bcl-2 family of proteins. The importance of this step is becoming increasingly relevant as the fir...More

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