Synthesis and antibacterial activity of 5-methoxy- and 5-hydroxy-6-fluoro-1,8-naphthyridone-3-carboxylic acid derivatives
Bioorganic & Medicinal Chemistry Letters（2005）
摘要
A series of 5-methoxy- and 5-hydroxy-6-fluoro-1,8-naphthyridone-3-carboxylic acid derivatives were prepared and evaluated for cell-free bacterial protein synthesis inhibition and whole cell antibacterial activity.
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关键词
Novel ribosome inhibitors,1,8-Naphthyridone antibiotics
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