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Skeletal-Muscle Proteasome Can Degrade Proteins In An Atp-Dependent Process That Does Not Require Ubiquitin

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, no. 3 (1989): 787-791

Cited: 59|Views24
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Abstract

The proteasome (the multicatalytic endoproteinase complex) in mammalian tissues hydrolyzes proteins and several types of peptides. When this structure was isolated rapidly from rabbit skeletal muscle in the presence of glycerol, its various peptidase and protease activities showed a large reversible activation by physiological concentrati...More

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