Slowly Progressive Dystonia Following Central Pontine And Extrapontine Myelinolysis
INTERNAL MEDICINE(2000)
摘要
A 28-year-old woman was hospitalized with dysarthria and oro-mandibular and upper limb dystonia. Approximately 8 years prior to the current admission, the woman became severely hyponatremic due to traumatic subarachnoid hemorrhage-related SIADH, Brain MRIs showed a signal increase in the central pens, thalamus and striatum on T2 weighted images compatible with central pontine and extrapontine myelinolysis. From a few months after that event, dystonia progressed slowly over the subsequent 8 years. We speculate that the particular damage chiefly to the myelin structures by myelinolytic process may have caused an extremely slow plastic reorganization of the neural structures. giving rise to progressive dystonia.
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关键词
demyelination, hyponatremia, pens, basal ganglia
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