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Motivational Responses to Natural and Drug Rewards in Rats with Neonatal Ventral Hippocampal Lesions An Animal Model of Dual Diagnosis Schizophrenia

Neuropsychopharmacology, no. 6 (2002): 889-905

Cited: 82|Views23

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pubmed.ncbi.nlm.nih.gov academic.microsoft.com www.sciencedirect.com

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Schizophrenia, Addiction, Dual diagnosis, Dopamine, Nucleus accumbens, Hippocampus

Abstract

The high prevalence of substance use disorders in schizophrenia relative to the general population and other psychiatric diagnoses could result from developmental neuropathology in hippocampal and cortical structures that underlie schizophrenia. In this study, we tested the effects of neonatal ventral hippocampal lesions on instrumental b...More

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R Andrew Chambers

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