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Induction of hTERT expression and telomerase activity by estrogens in human ovary epithelium cells.

MOLECULAR AND CELLULAR BIOLOGY, no. 11 (2000): 3764-3771

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In mammals, molecular mechanisms and factors involved in the tight regulation of telomerase expression and activity are still largely undefined. In this study, we provide evidence for a role of estrogens and their receptors in the transcriptional regulation of hTERT, the catalytic subunit of human telomerase and, consequently, in the acti...更多

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