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Structure Of Pyruvate Dehydrogenase Kinase - Novel Folding Pattern For A Serine Protein Kinase

JOURNAL OF BIOLOGICAL CHEMISTRY, no. 40 (2001): 37443-37450

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Abstract

The structure of mitochondrial pyruvate dehydrogenase kinase isozyme 2 is of interest because it represents a family of serine-specific protein kinases that lack sequence similarity with all other eukaryotic protein kinases. Similarity exists instead with key motifs of prokaryotic histidine protein kinases and a family of eukaryotic ATPas...More

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