Regulation Of Interleukin-6-Induced Hepatic Insulin Resistance By Mammalian Target Of Rapamycin Through The Stat3-Socs3 Pathway

The proinflammatory cytokine interleukin (IL)-6 has been proposed to be one of the mediators that link obesity-derived chronic inflammation with insulin resistance. Signaling through the mammalian target of rapamycin ( mTOR) has been found to impact insulin sensitivity under various pathological conditions, through serine phosphorylation ...更多