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Protein–DNA Hydrophobic Recognition in the Minor Groove is Facilitated by Sugar Switching

Journal of Molecular Biology, no. 1 (2004): 65-76

被引用72|浏览7
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Information readout in the DNA minor groove is accompanied by substantial DNA deformations, such as sugar switching between the two conformational domains, B-like C2′-endo and A-like C3′-endo. The effect of sugar puckering on the sequence-dependent protein–DNA interactions has not been studied systematically, however. Here, we analyzed th...更多

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