Pore region of TRPV3 ion channel is specifically required for heat activation

Jörg Grandl,Hongzhen Hu,Michael Bandell,Badry Bursulaya,Manuela Schmidt,Matt Petrus,Ardem Patapoutian

NATURE NEUROSCIENCE（2008）

引用 145|浏览7

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摘要

lthough certain ion channels can be gated by temperature, it is currently unknown how this occurs. Here, the authors identify regions of TRPV3 that are critical for heat sensation, yet independent of other channel gating mechanisms.

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关键词

trpv3 region channel,pore region

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