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Non-Steroidal Anti-Inflammatory Drugs Stimulate Secretion Of Non-Amyloidogenic Precursor Protein

JOURNAL OF BIOLOGICAL CHEMISTRY, no. 35 (2002): 31466-31473

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Chronic inflammatory processes are associated with the pathophysiology of Alzheimer's disease (AD), and it has been proposed that treatment with non-steroidal anti-inflammatory drugs (NSAIDs) reduces the risk for AD. Here we report that various NSAIDs, such as the cyclooxygenase inhibitors, nimesulide, ibuprofen and indomethacin, as well ...更多

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