Spatially precise DNA bending is an essential activity of the sox2 transcription factor.
The Journal of biological chemistry, no. 50 (2001): 47296-47302
Sox proteins, a subclass of high mobility group box proteins, govern cell fate decisions by acting both as classical transcription factors and architectural components of chromatin. We aimed to demonstrate that the DNA bending activity of Sox proteins is essential to regulate gene expression. We focused on mouse Sox2, which participates i...更多
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