Resolution of the mammalian E complex and the ATP-dependent spliceosomal complexes on native agarose mini-gels.
RNA, no. 11 (1999): 1504-1508
A great deal of progress in elucidating the mechanisms of spliceosome assembly has been achieved by analyzing the A, B, and C spliceosomal complexes on native polyacrylamide gels. In contrast, progress in understanding the earliest spliceosomal complex E has been hampered because this complex dissociates on native gels and is difficult to...更多
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