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Glyceraldehyde-3-phosphate dehydrogenase is a GABAA receptor kinase linking glycolysis to neuronal inhibition.

JOURNAL OF NEUROSCIENCE, no. 35 (2004): 7614-7622

Cited: 67|Views31

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pubmed.ncbi.nlm.nih.gov academic.microsoft.com

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GABA(A) receptor phosphorylationresponse rundownreceptor-associated kinaseGAPDHglycolysisMore(1+)

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Protein phosphorylation is crucial for regulating synaptic transmission. We describe a novel mechanism for the phosphorylation of the GABA(A) receptor, which mediates fast inhibition in the brain. A protein copurified and coimmunoprecipitated with the phosphorylated receptor alpha1 subunit; this receptor-associated protein was identified ...More

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