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Involvement of a Rac activator,P-Rex1, in neurotrophin-derived signaling and neuronal migration.

JOURNAL OF NEUROSCIENCE, no. 17 (2005): 4406-4419

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Rho-family GTPases play key roles in regulating cytoskeletal reorganization, contributing to many aspects of nervous system development. Their activities are known to be regulated by guanine nucleotide exchange factors ( GEFs), in response to various extracellular cues. P-Rex1, a GEF for Rac, has been mainly investigated in neutrophils, i...更多

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