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Refinements to label free proteome quantitation: how to deal with peptides shared by multiple proteins.

ANALYTICAL CHEMISTRY, no. 6 (2010): 2272-2281

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Quantitative shotgun proteomics is dependent on the detection, identification, and quantitative analysis of peptides. An issue arises with peptides that are shared between multiple proteins. What protein did they originate from and how should these shared peptides be used in a quantitative proteomics workflow? To systematically evaluate s...更多

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