The Slope of Circulating Blast Clearance Does Not Predict Disease Relapse after Allogeneic Stem Cell Transplantation

Leukemic relapse following initial induction chemotherapy has been predicted independently by the rate of peripheral blast clearance in adult AML and pediatric ALL. This early response to therapy in de-novo acute leukemia may indicate in-vivo chemosensitivity of malignant cells. No reports exist on whether blast response is predictive of relapse after myeloablative conditioning for allogeneic hematopoietic stem cell transplantation (AlloHSCT).