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Mechanically probing the folding pathway of single RNA molecules.
Biophysical Journal, no. 5 (2003): 2831-2840
We study theoretically the denaturation of single RNA molecules by mechanical stretching, focusing on signatures of the (un)folding pathway in molecular fluctuations. Our model describes the interactions between nucleotides by incorporating the experimentally determined free energy rules for RNA secondary structure, whereas exterior singl...More
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