Design, synthesis and SAR of a novel series of benzimidazoles as potent NPY Y5 antagonists

Bioorganic & Medicinal Chemistry Letters(2010)

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摘要
The synthesis and SAR of a series of potent NPY Y5 antagonists is reported. Optimisation led to the identification of compounds 9b (fpKi=9.2).
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关键词
NPY Y5,Benzimidazoles
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