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Origin Of Scaling Behavior Of Protein Packing Density: A Sequential Monte Carlo Study Of Compact Long Chain Polymers

JOURNAL OF CHEMICAL PHYSICS, no. 13 (2003): 6102-6109

Cited: 59|Views30

Abstract

Single domain proteins are thought to be tightly packed. The introduction of voids by mutations is often regarded as destabilizing. In this study we show that packing density for single domain proteins decreases with chain length. We find that the radius of gyration provides a poor description of protein packing but the alpha contact numb...More

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