Advantages and limitations of imaging the musculoskeletal system by conventional radiological, radionuclide, and hybrid modalities.

The endpoint of an efficient and accurate diagnosis of musculoskeletal pathology can take many different routes. Currently, conventional radiological techniques, such as plain radiography, ultrasonography, computed tomography, and magnetic resonance imaging are used in the assessment of patients with benign and malignant bone disease. An understanding of the advantages and limitations of the modalities available will help expedite diagnosis, and hence treatment. In this review, we discuss the advantages and limitations of the modalities available in investigating benign and malignant musculoskeletal pathology. Semin Nucl Med 39:357-368 (C) 2009 Published by Elsevier Inc.