Graft-Host Glutamatergic Neuronal Interaction in the Neocortex

V. V. Senatorov,I. Vilagi,I. Tarnawa,I. Banczerowski-Pelyhe,Z. Fulop

Neural plasticity（1992）

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摘要

Recent evidence indicates that grafts of fetal neocortical tissue develop reciprocal connec- tions with surrounding neocortical tissue of the host, but the nature of the neuromediator in these connections is still unclear.Excitatory synaptic transmission in the mammalian neo- cortex activated by glutamate is mediated by both N-methyl-D-aspartate (NMDA) and non- NMDA receptors.The non-NMDA receptor- channel complex mediates a fast voltage- independent synaptic conductance, while the

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