Intraparenchymal hemorrhage in a pregnant patient with neurocysticercosis

Incidentally discovered diffusely infiltrating low-grade gliomas (iDLGGs) are rare findings on neuroimaging that pose a challenge to neurosurgeons. There is a paucity of data regarding the natural history of these lesions, and thus management is controversial. We characterize the growth rates and patterns of iDLGGs in a cohort of patients who underwent serial magnetic resonance imaging before surgical treatment.We performed a retrospective review of all adult patients (≥18 years old) with diffuse low-grade glioma diagnosed at our institution between April 2004 and April 2016. iDLGG was defined as any lesion discovered on computed tomography or magnetic resonance imaging performed for reasons and/or symptoms not attributable to the lesion and confirmed on histopathology as low-grade glioma. Tumor growth rates and patterns of growth were analyzed in patients who had serial imaging available.Inclusion criteria were met by 15 patients. Mean velocity of diametric expansion was 2.93 mm/year. Of 15 patients, 11 (73.3%) had tumors with an exponential growth pattern, and 4 (26.7%) had a linear growth pattern. Initial tumor volume was positively correlated (r = 0.78) with velocity of diametric expansion.iDLGGs grow over time, and most exhibit an exponential pattern of growth. Tumor volume at the time of diagnosis is predictive of a faster growth rate, but not the pattern of growth.