Surgical Apgar Score Predicts Perioperative Morbidity in Patients Undergoing Pancreaticoduodenectomy at a High-Volume Center

GASTROENTEROLOGY(2011)

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摘要
Objectives Pancreaticoduodenectomy (PD) remains a procedure that carries considerable morbidity. Numerous studies have evaluated factors to predict patients at risk. The aim of this study was to determine whether the surgical Apgar score (SAS) predicts perioperative morbidity and mortality. Methods We examined 553 patients undergoing successful PD between January 2000 and December 2010. Postoperative complications were graded using the Clavien scale, and the SAS (range, 0–10) was determined. The Cochran–Armitage test for trend was used to determine the association between grouped SAS scores (0–2, 3–4, 5–6, 7–8, and 9–10) and each of the outcomes. Results The average patient age was 64 years, and there was an even distribution of males and females. There were 11 perioperative deaths (2%), 186 grade 2 or higher complications (34%), and 86 major complications (grades 3–5, 16%). Additionally, 61 patients developed pancreatic fistulae (11%). Statistical analysis determined that SAS was a significant predictor of grade 2 or higher complications ( p < 0.0001), major morbidity ( p = 0.01), and pancreatic fistula ( p = 0.04) but not mortality ( p = 0.20). Conclusions We demonstrate that the SAS is a significant predictor of perioperative morbidity for patients undergoing PD. This score should be used to identify patients at higher risk in order to prioritize use of postoperative critical care beds and hospital resources.
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关键词
Pancreaticoduodenectomy,Complications,Surgical Apgar
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