Glutathione S-transferase P1 has protective effects on cell viability against camptothecin.

Takamitsu Hara,Takeo Ishii,Mina Fujishiro,Michiaki Masuda,Takaaki Ito,Jun Nakajima,Tomio Inoue,Takeshi Matsuse

Cancer Letters（2004）

引用 12|浏览6

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摘要

Glutathione S-transferase P1 (GSTP1) is one of the important xenobiotic-metabolizing enzymes. It was reported that GSTP1 was overexpressed in malignant tissues, and its expression level was associated with resistance to chemotherapeutics.

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关键词

Glutathione S-transferase P1,Camptothecin,Cell cycle arrest,Apoptosis

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