Stereoselective Synthesis Of Novel C-Disaccharides Via Suzuki Cross-Coupling Reactions

Novel beta-C-disaccharides containing a three carbon linkage using exo-glycal as the precursor were prepared stereoselectively. The synthesis was achieved by the tandem reactions of the stereoselective hydroboration of exo-glycal and Suzuki cross-coupling reaction with an iodovinyl sugar, and followed by hydrogenated deprotection under the catalysis of Pd(OH)(2)/C.