ChemInform Abstract: A Novel Synthesis of 2-Fluoroalkyl Quinolines.

2-Fluoroalkyl quinolines are prepared by reacting aniline with α-fluoroalkyl aldehydes or α-fluoroalkyl cyclohexanones in the presence of acetic acid. Under the same reaction condition, 2-aminophenol gives the corresponding 2-fluoroalkyl-8-quinolinols; in some cases, 2-fluoroalkyl benzoxazoles are also formed as minor products.